Apical potassium (BK) channels and enhanced potassium secretion in human colon.
نویسندگان
چکیده
The human colon has the capacity to secrete potassium (K(+)) ions and enhanced K(+) secretion is a feature of a variety of diarrhoeal diseases. Recent work points to K(+) secretion in human colon being mediated by high conductance (BK) K(+) channels located in the apical membrane of colonic epithelial cells. The aim of this review is to highlight the importance of these channels in maintaining K(+) homoeostasis in health and disease.
منابع مشابه
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عنوان ژورنال:
- QJM : monthly journal of the Association of Physicians
دوره 103 2 شماره
صفحات -
تاریخ انتشار 2010